Search results for "blood [Encephalitis]"

The challenges of analysing blood stains with hyperspectral imaging

2014

Hyperspectral imaging is a potential noninvasive technology for detecting, separating and identifying various substances. In the forensic and military medicine and other CBRNE related use it could be a potential method for analyzing blood and for scanning other human based fluids. For example, it would be valuable to easily detect whether some traces of blood are from one or more persons or if there are some irrelevant substances or anomalies in the blood. This article represents an experiment of separating four persons' blood stains on a white cotton fabric with a SWIR hyperspectral camera and FT-NIR spectrometer. Each tested sample includes standardized 75 _l of 100 % blood. The results s…

Longitudinal and cross-sectional associations of adherence to 24-hour movement guidelines with cardiometabolic risk

2022

This study aimed to examine 1) adherence to 24-hour movement guidelines over a 2-year follow-up in children aged 6-8 years and 2) association of this adherence with cardiometabolic risk factors. Physical activity and sleep were assessed by a monitor combining heart rate and accelerometry measurements. Screen time was reported by the parents. Body fat percentage, waist circumference, blood glucose, serum insulin, plasma lipids and blood pressure were assessed, and a cardiometabolic risk score was calculated using z-scores. Children were classified as meeting the guidelines if they had on average ≥60min/day of moderate-to-vigorous physical activity during the valid days; ≤120min/day of screen…

Intravenous iron therapy in patients with heart failure. A double-edged sword

2013

We read with interest the article of Beck-da-Silva et al., who recently concluded that intravenous (IV) iron seems to be superior over oral supplementation for improving functional capacity of heart failure patients [1]. Irrespective of the study design, involving comparison of functional outcomes between two different means of iron supplementation, we raise some clinical issues about the rationale underlying this investigation. According to the data published by Beck-da-Silva et al., the modest number of patients (n = 23) enrolled in this multicenter investigation had moderate anemia (i.e., hemoglobin concentration comprised between 90 and 120 g/L) but no evidence of iron deficiency, which…

Impacto del quimerismo hematopoyético precoz en el injerto tras trasplante alogénico de progenitores de sangre de cordón umbilical de donante no empa…

2013

El trasplante de sangre de cordón umbilical (TSCU) ha experimentado un auge muy importante en los últimos años como alternativa a la médula ósea y sangre periférica, debido a la dificultad de encontrar donantes altruistas de estas fuentes de progenitores hematopoyéticos. Los datos clínicos disponibles hasta la fecha muestran una supervivencia libre de enfermedad similar a la observada con el trasplante de médula ósea (TMO) o sangre periférica (TSP). Sin embargo, como consecuencia de la baja dosis celular contenida en la SCU, la tasa de fallo de injertos es más elevada y el tiempo hasta la recuperación de la neutropenia más prolongado. Gran parte de la investigación en el terreno del TSCU se…

Vascular Aging effect on Medial aorta degeneration: focus on blood keukocyte telomere lenght in Hypertensive and old patients with sporadic thoracic …

2012

Platelet cut-off for anticoagulant therapy in thrombocytopenic patients with blood cancer and venous thromboembolism: an expert consensus

2019

Background. Management of venous thromboembolism (VTE) in patients with haematologic malignancies and thrombocytopenia is clinically challenging due to the related risks. No prospective studies or clinical trials have been carried out and, therefore, no solid evidence on this compelling issue is available. Methods. Given this, an expert panel endorsed by the Gruppo Italiano Malattie Ematologiche dell'Adulto Working Party on Thrombosis and Haemostasis was set up to produce a formal consensus, according to the RAND method, in order to issue clinical recommendations about the platelet (PLT) cut-off for safe administration of low molecular weight heparin (LMWH) in thrombocytopenic (PLT <100×…

Acute arterial stiffness, testosterone and force production responses and recovery from different combined strength and endurance loading models

2017

Much of the differences between strength (S) and endurance (E) exercise can be attributed to the contrasting endocrinological and molecular responses between the two exercise modes. From the current literature, it seems that aortic arterial stiffness, a reliable cardiovascular mortality predictor, also responds differently to these two modes of exercise. It is thus important to understand the acute responses that combined exercise loads may invoke, as acute responses are known to drive chronic adaptations. Furthermore, testosterone has been cited as a key hormone in cardiovascular protection and its effects may mediate blood flow and hemodynamics. Currently, there are very few studies inves…

Translocation of the nuclear autoantigen La to the cell surface of herpes simplex virus type 1 infected cells.

1992

Recently we developed a procedure to translocalize one of the extractable nuclear antigens (ENAs), the La protein, to the cell surface of CV-1 cells. Here we report that herpes simplex virus type 1 infection can also induce a translocation of the autoantigen to the cell surface. On the cell surface we detected La protein assembled with large protrusions. Within these protrusions La protein colocalized with virus particles. These protrusions are known to be released from the cell after virus infections. Such complexes consisting of self and virus could provide helper determinants for an anti-self response, and therefore be important in generation of autoimmunity.

Longitudinal physical activity patterns and the development of cardiometabolic risk factors during adolescence

2023

Purpose To examine the associations between longitudinal physical activity (PA) patterns and the development of cardiometabolic risk factors from adolescence to young adulthood. Methods This cohort study encompassed 250 participants recruited from sports clubs and schools, and examined at mean age 15 and 19. Device-measured moderate-to-vigorous PA was grouped into five patterns (via a data-driven method, using inactivity maintainers as a reference). The outcomes were: glucose, insulin, homeostasis model assessment for insulin resistance (HOMA-IR), total cholesterol, HDL and LDL cholesterol, triglycerides, blood pressure, and body mass index (BMI). Linear growth curve models were applied wit…